working memory

A dopamine gradient controls access to distributed working memory in the large-scale monkey cortex

Dopamine is required for working memory, but how it modulates the large-scale cortex is unknown. Here, we report that dopamine receptor density per neuron, measured by autoradiography, displays a macroscopic gradient along the macaque cortical …

White matter alterations to cingulum and fornix following very preterm birth and their relationship with cognitive functions

Very preterm birth (VPT; <32 weeks of gestation) has been associated with impairments in memory abilities and functional neuroanatomical brain alterations in medial temporal and fronto-parietal areas. Here we investigated the relationship between …

Plasticity in the Working Memory System: Life Span Changes and Response to Injury

Alterations in development of hippocampal and cortical memory mechanisms following very preterm birth

Deficits in memory function have been described in children and adolescents who were born very preterm (VPT), which can have profound effects on their school achievement and everyday life. However, to date, little is known about the development of …

Very Early Brain Damage Leads to Remodeling of the Working Memory System in Adulthood: A Combined fMRI/Tractography Study

Children who have brain injury following preterm birth often have working memory problems. When we assessed adults with the same injury, we found they no longer had severe working memory difficulties. By combining techniques to investigate the …